SLC11A1

SLC11A1 est un gène situé sur le chromosome 2 humain.

SLC11A1
Identifiants
Alias	SLC11A1
IDs externes	OMIM: 600266 MGI: 1345275 HomoloGene: 73884 GeneCards: SLC11A1
Position du gène (humain) Chr. Chromosome 2 humain Locus 2q35 Début 218,382,029 bp Fin 218,396,894 bp
Position du gène (souris) Chr. Chromosome 1 (souris) Locus 1 C3|1 38.54 cM Début 74,414,354 bp Fin 74,425,221 bp
Expression génique Bgee Humain Souris (orthologue) Fortement exprimé dans poumon droit upper lobe of left lung granulocyte monocyte sang rate buccal mucosa cell left uterine tube left adrenal cortex cellule de la moelle osseuse Fortement exprimé dans granulocyte stroma of bone marrow rate artère carotide interne ganglion mésentérique tibiofemoral joint morula corps ciliaire sang corpuscule carotidien Plus de données d'expression de référence BioGPS Plus de données d'expression de référence
Gene Ontology Fonction moléculaire manganese ion transmembrane transporter activity protein homodimerization activity transition metal ion transmembrane transporter activity metal ion:proton antiporter activity metal ion transmembrane transporter activity cadmium ion transmembrane transporter activity iron ion transmembrane transporter activity Composant cellulaire integral component of membrane late endosome phagocytic vesicle membrane membrane late endosome membrane integral component of plasma membrane lysosome endosome membrane membrane plasmique tertiary granule membrane ficolin-1-rich granule membrane Processus biologique manganese ion transmembrane transport interleukin-3 production positive regulation of phagocytosis response to bacterium response to interferon-gamma positive regulation of cytokine production iron ion homeostasis positive regulation of interferon-gamma production cicatrisation ion transport cellular cadmium ion homeostasis cell redox homeostasis T cell proliferation involved in immune response vacuolar acidification explosion respiratoire multicellular organismal iron ion homeostasis mRNA stabilization response to lipopolysaccharide antigen processing and presentation of peptide antigen positive regulation of dendritic cell antigen processing and presentation positive regulation of gene expression iron ion transport defense response to bacterium positive regulation of T-helper 1 type immune response MHC class II biosynthetic process defense response to Gram-negative bacterium cadmium ion transmembrane transport phagocytose manganese ion transport nitrite transport macrophage activation réponse inflammatoire T cell cytokine production interleukin-2 production negative regulation of cytokine production activation of protein kinase activity positive regulation of transcription by RNA polymerase II cellular iron ion homeostasis defense response to protozoan antimicrobial humoral response neutrophil degranulation metal ion transport iron ion transmembrane transport Sources:Amigo / QuickGO
Orthologues Espèces Homme Souris Entrez 6556 18173 Ensembl ENSG00000018280 ENSMUSG00000026177 UniProt P49279 P41251 RefSeq (mRNA) NM_000578 NM_001032220 NM_013612 RefSeq (protéine) NP_000569 NP_038640 Localisation (UCSC) Chr 2: 218.38 – 218.4 Mb Chr 1: 74.41 – 74.43 Mb Publication PubMed
Wikidata
Voir/Editer Humain Voir/Editer Souris

Maladies liées

• Tuberculose
• Mucovicidose